Humidity response in Drosophila olfactory sensory neurons requires the mechanosensitive channel TMEM63

2022-07-06

Humidity response in Drosophila olfactory sensory neurons requires the mechanosensitive channel TMEM63

Thus, our results reveal a role of Tmem63 in hygrosensation and support the strategy to detect humidity by transforming it into a mechanical stimulus, which is unique in sensory transduction.

A volatile from the skin microbiota of flavivirus-infected hosts promotes mosquito attractiveness

2022-07-05

A volatile from the skin microbiota of flavivirus-infected hosts promotes mosquito attractiveness

Given that RELMα can be specifically induced by a vitamin A derivative, the dietary administration of isotretinoin to flavivirus-infected animals interrupted flavivirus life cycle by reducing mosquito host-seeking activity, thus providing a strategy of arboviral control.

Neuroligin-3 confines AMPA receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses
Microfluidic Platform for Time-Resolved Characterization of Protein Higher-Order Structures and Dynamics Using Top-Down Mass Spectrometry

2022-06-21

Microfluidic Platform for Time-Resolved Characterization of Protein Higher-Order Structures and Dynamics Using Top-Down Mass Spectrometry

This strategy may benefit elaborate structural analysis of biomacromolecules and inspire method development using the microchip-MS approach.

Lipases secreted by a gut bacterium inhibit arbovirus transmission in mosquitoes

2022-06-21

Lipases secreted by a gut bacterium inhibit arbovirus transmission in mosquitoes

The anti-arboviral and entomopathogenic properties of CbAEs render them potential candidates for the development of novel transmission control strategies against vector-borne diseases.

Therapeutic potential for amyloid surface inhibitor: Only Amyloid-β oligomers formed by secondary nucleation disrupt lipid membrane integrity