Research Areas

The research field covers fusion protein design, enzyme engineering, biobreeding technology and instrumentation, high throughput technology, organoid microfluidic system, health-care product engineering and glycodrug technology.

Highlights

During the past two decades, Prof. Xing has developed the atmospheric and room temperature plasma (ARTP) mutation breeding technology and the ARTP biological breeding equipment has been successfully applied in scientific research and biological industry, and exported to overseas. Before joining Tsinghua University in 2001, he had worked in universities of Japan for ten years. He was awarded the Fellow of School of engineering, the University of Tokyo in 2018. He served as the director of China Biotech Fermentation Industry Association and vice chairman of microbial breeding branch and also served as the associate editor of Biological Engineering Journal and Editorial Committee of many other domestic and international academic journals in the field of biochemistry. He has more than 320 publications and obtained more than 80 authorized invention patents. Since 2014, he has been continuously selected as a highly cited scholar of Elsevier in China. In 2009, he won the second prize of technological innovation award of China Petroleum and Chemical Industry Association. In 2010, he was awarded the Creative Talent of China Federation of Returned Overseas Chinese. He won the Science Technology Achievement Award, Higher Institutions of MOE (2015), Gold Medal of The 45th Geneva International Inventions (2017), and First Prize of Technological Invention of China National Light Industry Associations (2019). As PI or Co-PI, 19 grants have been funded by National Science Fundation of China, Minstry of Science and Technology, International Projects and university-funded  projects, and 10 projects have been supported by industries including international companies on environmental microbiology, industry biotechnology, bioenergy. 

Professor Teruyuki Nagamune, former director of the Department of bioengineering, University of Tokyo, awarded the fellow memorial to Xing Xinhui, 2018.

Honors

• Research award of TEJIMA INDUSTRIAL EDUCATION FOUNDATION of Japan (1992)

• Award of Good Teacher and helpful friend of Tsinghua University (2002)

• Award of Takeda International Academic Exchange (2004)

• Silver award of the 17th National Invention Exhibition (2007)

• Beijing Science and Technology Award (2008)

• Technological invention award of China Petroleum and Chemical Industry Association (2009)

• Creative Talent of China Federation of Returned Overseas Chinese (2010)

• Science Technology Achievement Award, Higher Institutions of MOE (2015)

• Award of advanced individuals in international cooperation and exchange of Tsinghua University (2016)

• Gold Medal of The 45th Geneva International Inventions (2017)

• Thailand award for best international invention awarded by National Research Council of Thailand (2017)

• Award of advanced individuals from 2012 to 2017 by The Chemical Industry and Engineering Society of China (2017)

• Fellow, School of Engineering, The University of Tokyo (2018)

• Fellow, Tokyo Institute of Technology, Japan (2019)

• Fellow Award of The International Bioprocessing Association (IBA)(2019)

• First Prize of Technological Invention of China National Light Industry Associations (2019)

Selected Publications

1. Wen Zeng, Dong He, Yifan Xing, Junyu Liu, Nan Su, Chong Zhang, Yi Wang*, Xinhui Xing*, Internal connections between dietary intake and gut microbiota homeostasis in disease progression of ulcerative colitis: a review. Food Science and Human Wellness, 10, 119-130 (2021)

2. Wang, TM (Wang, Tianmin)#,* ; Zheng, X (Zheng, Xiang)# ; Ji, HN (Ji, Haonan); Wang, TL (Wang, Ting-Liang); Xing, XH (Xing, Xin-Hui); Zhang, C (Zhang, Chong)*， Dynamics of transcription-translation coordination tune bacterial indole signaling. Nature Chemical Biology, 16, 440-449 (2020)

3. Tan, ZL (Tan, Zheng Lin); Zheng, X (Zheng, Xiang); Wu, YA (Wu, Yinan); Jian, XJ (Jian, Xingjin); Xing, XH (Xing, Xinhui); Zhang, C (Zhang, Chong)*, In vivo continuous evolution of metabolic pathways for chemical production. Microbial Cell Factory, 18: 82 (2019)

4. Tianmin Wang^##, Changge Guan^##, Jiahui Guo, Bing Liu, Yinan Wu, Zhen Xie, Chong Zhang*, and Xin-Hui Xing, Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance. Nature Communications, 9, 2475 (2018)

5. Shu-De Liu^##, Yi-nan Wu^##, Tian-Min Wang, Chong Zhang* and Xin-Hui Xing, Maltose utilization as a novel selection strategy for continuous evolution of microbes with enhanced metabolite production. ACS Synthetic Biology, 6(12), 2326–2338 (2017)