Institute of Biomedical Health Technology and Engineering
Junior Principal Investigator
2020 - Present
Shenzhen Bay Laboratory Junior Principal Investigator
2019 - 2020
National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health (NIH) Postdoc
2018 - 2019
Simmons Comprehensive Cancer Center, UT Southwestern Medical Center Postdoc
2013 - 2018
Wuhan University PhD
2009 - 2013
Wuhan University Bachelor
My research aims to create cutting-edge biomimetic nanotechnology and exploit them to study and solve complex biological problems that are associated with human diseases. One major research goal is to overcome the various therapeutic barriers in the treatment of cancer and viral infection. I also seek to understand the fundamental sciences at the interface of nanomedicine and biology. Overall, my research program covers a broad scope of multidisciplinary areas including chemistry, materials science, nanotechnology, biotechnology and medicine.
• 2022 Excellent Youth Fund, National Science Foundation of China
• 2022 May-First Labor Medal, Shenzhen
• 2021 Overseas High-Caliber Personnel, Shenzhen
• 2017 Future Scientist Award, Biomaterials
1. D. Wu*, K. Yang, L. Rao*, X. Chen*, & G. Yu*. Metal-free bioorthogonal click chemistry in cancer theranostics. Chem. Soc. Rev., 2022, 51, 1336-1376.
2. Q.-F. Meng, Y. Zhao, C. Dong, Y. Pan, L. Liu, J. Lai, Z. Liu, G.-T. Yu*, X. Chen*, & L. Rao*. Genetically Programmable Fusion Cellular Vesicles for Cancer Immunotherapy. Angew. Chem. Int. Ed., 2021, 60, 26320-26326.
3. Q.-F. Meng, R. Tian, H. Long, X. Wu, J. Lai, O. Zharkova, J.-W. Wang*, X. Chen*, & L. Rao*. Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm. Adv. Mater., 2021, 33, 2100012.
4. L. Rao, S. Xia, W. Xu, R. Tian, G. Yu, C. Gu, P. Pan, Q.-F. Meng, X. Cai, D. Qu, L. Lu*, Y. Xie*, S. Jiang*, and X. Chen*. Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines. Proc. Natl. Acad. Sci. USA, 2020, 117, 202014352. (Featured as Cover; Highlighted by The Scientist; Chemistry Views; Inverse; Infosurhoy; Scitech Daily).
5. L. Rao, L. Wu, Z. Liu, R. Tian, G. Yu, Z. Zhou, K. Yang, H.-G. Xiong, A. Zhang, G.-T. Yu, W. Sun, H. Xu, J. Guo, A. Li, H. Chen*, Z.-J. Sun*, Y.-X. Fu*, & X. Chen*. Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis. Nat. Commun., 2020, 11, 4909.