Transposable elements (TEs) are abundant in metazoan genomes and have multifaceted effects on host fitness. However, the mechanisms underlying the fun...
2023-03-07
A generalizable strategy with programmable site specificity for in situ profiling of histone modifications on unperturbed chromatin remains highly des...
2023-03-07
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been on a rampage for more than two years. Vaccines in combination with neutral...
2023-02-27
A cryo–electron microscopy structure of menin bound to an H3K79me2 nucleosome revealed that menin engages with the nucleosome using its fingers and pa...
2023-02-25
While 1,1-diboryl (gem-diboryl) compounds are valuable synthetic building blocks, currently, related studies have mainly focused on those 1,1-diboryl ...
2023-02-08
Our work sheds light on the molecular basis of cfDNA fragmentation towards broader applications in cancer liquid biopsy....
2023-02-01
In a sequential trace conditioning paradigm, this serotonergic neuromodulation helps to bridge the CS-US temporal gap. Altogether, we report a model c...
2023-01-30
The spatiotemporal control of O-GlcNAc through the chemically activatable OGA–intein fusion will facilitate the manipulation and functional understand...
2023-01-17
The induced BAs can not only enhance the imaging signals at target genomic loci using a single sgRNA, either at repetitive or non-repetitive sequences...
2023-01-13
