Research Areas

Coming soon……

Honors

1991    Shen-Shou Chun Experimental Physics Prize, Nankai University, China 

2000    18th Jerzy E. Rose Neuroscience Award for original and significant research in the neuroscience, UW - Madison

Selected Publications

1. Zhang X, Wu R, Liu Q, Zhou L*.

Interfacial water molecules contribute to antibody binding to the receptor-binding domain of SARS-CoV-2 spike protein.

J Biomol Struct Dyn. 2023 Apr 12:1-10.

 2. Yao R, Hou J, Zhang X, Li Y, Lai J, Wu Q, Liu Q, Zhou L*.

Targeted photodynamic neutralization of SARS-CoV-2 mediated by singlet oxygen.

Photochem Photobiol Sci. 2023 Feb 8:1-18.

3. Shah N, Zhou L*.

Regulation of Ion Channel Function by Gas Molecules.

Adv Exp Med Biol. 2021;1349:139-164. PMID: 35138614 Review.

4. Wei F, Wang Q, Han J, Goswamee P, Gupta A, McQuiston AR, Liu Q, Zhou L*.

Photodynamic modification of native HCN channels expressed in thalamocortical neurons.

ACS Chem Neurosci. 2020 Feb 20; 11(6):851-863.

5. Idikuda V, Gao W, Grant K, Su Z, Liu Q, and Zhou L*

State-dependent binding of cAMP to closed, inactivated, and open sea urchin HCN channels.

Journal of General Physiology. 2019 Feb 4;151(2):200-213. PMID: 30541772 Dec 12.

6. Idikuda V, Gao W, Grant K, Su Z, Liu Q, and Zhou L*

Singlet oxygen modification abolishes voltage-dependent inactivation in sea-urchin hyperpolarization-activated cyclic nucleotide-gated (spHCN) channel.

Journal of General Physiology. 2018 Sep 3;150(9):1273-1286.018.

7. Zhu M, Idikuda V, Wang J, Wei F, Kumar V, Shah N, Waite CB, Liu Q, Zhou L*.

Shank3-deficient thalamocortical neurons show HCN channelopathy and alterations in intrinsic electrical properties.

Journal of Physiology. 2018 Apr 1;596(7):1259-1276.

8. Liu C, Xie C, Grant KL, Su Z, Gao W, Liu Q, Zhou L*.

Determine the unitary conductance of HCN channels by a channel counting method based on patch-clamp fluorometry

Journal of General Physiology. 2016 Jul;148(1):65-76.

9. Gao W, Su Z, Liu Q, Zhou L*

State-dependent and site-directed photodynamic transformation of HCN2 channel by singlet oxygen.

Journal of General Physiology. 2014 May;143(5):633-44.

10. Zhou L*, Liu Q.

Aligning experimental and theoretical anisotropic B-factors: water models, normal-mode analysis methods, and metrics.

Journal of Physical Chemistry B. 2014 Apr 17;118(15):4069-79.