The Institute of Infectious Diseases in Shenzhen Bay Laboratory was established in August 2020. Positioned at the intersection of basic research, public health, and clinical studies, this pioneering institute is devoted to shaping foundational theories and spearheading the development of novel vaccines and therapeutic drugs. The institute strategically focuses on the following areas: Detection and diagnosis of potential epidemic pathogens, Investigation of etiology and genetic evolution of infectious diseases, Delving into the infection dynamics and immune mechanisms of infectious diseases, and Innovations in vaccines and therapies for infectious diseases. Dedicated to addressing the significant theoretical and technological challenges in the field of infectious diseases, the institute adeptly merges research, clinical practices, and translational medicine. This integrated approach aims to provide technological backing and strategic reserves for the prevention, diagnosis, treatment, and emergency response to major infectious diseases in China.